Qatar vinyl company ltd.
What are the target organ of vinyl chloride.
In 1974 vinyl chloride vc was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals.
Vinyl chloride is an organochloride with the formula h 2 c chcl that is also called vinyl chloride monomer vcm or chloroethene this colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride pvc.
Synonyms trade names chloroethene chloroethylene ethylene monochloride monochloroethene monochloroethylene vc vcm vinyl chloride monomer vcm.
Target organs liver central nervous system blood respiratory system lymphatic system cancer site liver cancer.
About 13 billion kilograms are produced annually.
Target organ effect the target organs and potential effects of vinyl chloride exposure include.
Additional research has now demonstrated the carcinogenicity of vc to other organs and at lower concentrations.
It has a faint sweet odor.
Makarov et al 1984.
The cns is the primary target of vinyl chloride acute toxicity.
12 10 2017 01 identification of the substance preparation and the company undertaking product name vinyl chloride monomer sds no.
When confined under high pressure in special containers vinyl chloride exists in a liquefied state.
The primary route of vinyl chloride exposure is inhalation.
At room temperature vinyl chloride is a colorless highly flammable potentially explosive gas.
The following is a target organ categorization of effects which may occur from exposure to hazardous chemicals including examples of signs and symptoms and.
003 manufacturer emergency telephone no.
There may be a latent period of hours to days between exposure and symptom onset.
The reader is referred to section 3 2 discussion of health effects by route of exposure for additional information on other effects.
Noncancerous hepatotoxicity and carcinogenicity of vinyl chloride are discussed in greater detail below.
The liver appears to be the most sensitive target organ of vinyl chloride.
It is shipped and handled this way.
The odor threshold for vinyl chloride is about 3 000 ppm in air depending on the individual.
Vinyl chloride is thought to depress the cns via a solvent effect on lipids and protein components of neural membranes that interrupt signal transmission.
For the oral route of exposure the primary target organ of vinyl chloride toxicity in animals is the liver.
The target organs for vc now clearly in.
Accidental ingestion may be possible when eating or smoking with contaminated hands.
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Toxins do not affect all organs in the body to the same extent due to their different cell structures.
Table 1 target organs and potential effects of vinyl chloride exposure target organ effect.
